Studies on Abnormal
نویسنده
چکیده
Recently, ithas been demonstrated thatthe offspring of one parent with the sickle cell trait and one w’ith thalassemia may develop a severe hemolytic anemia with some of the characteristics of both thalassemia and sickle cell disease, ineluding microcytosis and numerous sickled erythrocytes in the blood film. This syndrome has been called mi(’rodrepanocytic,9 or sickle cell-thalassemia, disease)#{176}”2 Although only one gene for the abnormal sickle cell (S) hemoglobin is transmitted, the hemolysates prepared from the erythrocytes of patients with microdrepanocytosis contain 60 to 80 per cent S hemoglobin.’2 13
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